What challenges are encountered in selecting appropriate internal standards for preclinical toxicology studies?
Master Preclinical Toxicology with HRMS
Predict Toxicity Earlier in Development
HRMS enhances quantitative bioanalytical studies, including biomarker analysis & validation, enriching drug metabolism and pharmacokinetic (DMPK) assessments, and time profiles. It enables you to achieve the sensitivity and precise calibration necessary to accurately reflect both subtle and significant effects of your products on endogenous molecules at preclinical stages of development.
Overcome Matrix Effects
Discover Expert Methods
With 17 years of experience in supporting emerging and mid-size Pharma and Biotech from preclinical through clinical phases, Sannova Analytical, a leading contract research organization (CRO), has developed 300+ validated methods across 21 species and matrices. Our whitepaper is a valuable guide for pharmaceutical and biotech developers seeking to extend the lower limit of quantification to measure endogenous molecules and select the right method for traditional and biological drug development.